Fabrice di Falco, born to an Italian father in Martinique (France), moved to Paris in order to perfect his exceptional voice, following Barbara Hendricks' advice who had attended the 19-year old male soprano’s first solo concert in the Saint-Louis Cathedral of Fort-de-France in Martinique. In Paris, he was admitted to Liliane Mazeron’s class at the National Conservatory in Boulogne-Billancourt, finishing his studies in June 1999 with a first prize.

In 2000, he participated in a masterclass for interpretation with the renowned baroque specialist Gérard Lesne at the Abbey of Royaumont. During that same period, he started into his professional career, singing the roles of Cupido in Haendel's "Semele", Sextus in "Giulio Cesare" and Nero in "The Coronation of Poppea" by Monteverdi, under the baton of Patrick Bismuth and Laure Morabito.

In 2003, he entered the Atelier Lyrique de Tourcouing to sing the role of Narciso in Haendel's "Agrippina" under the baton of Jean-Claude Malgoire, directed by Fréderic Fisbach, at the sides of Véronique Gens, and Philippe Jaroussky.

Fabrice di Falco also focusses on contemporary music: Peter Ruzicka invites him to sing one of the main characters, the androgyne Magician, in the world premiere of Gerhard Winkler's opera "Heptameron" in the framework of the Munich Biennale and the ZKM Karlsruhe in 2002. In 2004 he sings the role of Diouf in the world premiere of "Les Nègres", an opera by Michael Levinas after a drama by Jean Genet, performed at the Opéra de Lyon and the Opera of Geneva under the baton of Bernhard Kontarsky, directed by Stanislas Nordey. Later on, Fabrice di Falco studies the role of Adschib in Henze's "Upupa" as a cover for Axel Köhler at the Teatro Real in Madrid under Gérard Korsten, returns to the Opera de Lyon to sing Adschib there, as well as at the Suntory Hall in Tokyo with the Tokyo Symphony Orchestra.

The opera "Piranhas" by Florence Baschet under the baton of Jean-Paul Odiau, as well as the role of a Bird in Levinas' "La Conférence des oiseaux" in Venice under the baton of Mark Foster further strengthen Fabrice's reputation for contemporary works.

He also regularly performs with the harpsichord-player Hughette Gremy-Chauliac in various baroque programmes, such as Vivaldi's "Stabat Mater" and Pergolesi's "Salve Regina". Fabrice di Falco is a demanded guest in French and international festivals, among others the Festival Présences Multiphonies de Radio France, the Festival de Royaumont, the Festival Nord Bourgogne, the Festival du Comminges, the Young Euro Classics Festival at the Konzerthaus in Berlin, the festival "300 years St. Petersburg", the Festival "C'est pas classique" in Nice, as well as in Japan, England, Italy, Austria, in the Antilles, Tunisia and in Senegal.
Fabrice who has always been fascinated by the Jazz, also performed with the African saxophone player Manu Dibango, including the concert at the famous "Olympia" in Paris where he made his audience discover his passion for baroque singing.

Successful appearances of Fabrice di Falco were the role of Oberon in Britten's "A Midsummernight's Dream" at the Teatro Colon in Buenos Aires (Argentina) in 2006 and in Nice (France) in 2008. During 2008/09, Fabrice di Falco performed the main character of Fougère Goldwashing in the world premiere of "Les quatre jumelles" by Régis Campo directed by Laurent Cuniot in various French Opera Houses, which was greatly applauded by audiences and critics.

In september 2009, Fabrice sang a highly applauded concert with the Kuopio Symphony Orchestra in Finland under the baton of Grant Llewellyn with arias by Purcell, Gluck, Haendel and Mozart.

His first solo CD released by the JVC Corporation in 1999, with the title "Ombra mai fu", was later followed by CD recordings of various operas: "Heptameron" by Winkler, "Les Nègres" by Lévinas, "Agrippine" by Haendel, and in 2009, "Les quatre jumelles" by Campo.